21BQ

Cryo-EM structure of ex vivo Sup35 prion fibrils from yeast carrying "strong" [PSI+] variant

Summary for 21BQ

Entry DOI	10.2210/pdb21bq/pdb
EMDB information	67558
Descriptor	Amyloid of yeast prion Sup35 (1 entity in total)
Functional Keywords	amyloid, prion, yeast, in vivo, natural, protein fibril
Biological source	Saccharomyces cerevisiae
Total number of polymer chains	5
Total formula weight	89977.19
Authors	Chesnokov, Y.M.,Burtseva, A.D.,Dergalev, A.A.,Baimukhametov, T.N.,Kushnirov, V.V.,Popov, V.O.,Boyko, K.M. (deposition date: 2025-12-06, release date: 2026-07-22, Last modification date: 2026-09-30)
Primary citation	Dergalev, A.A.,Chesnokov, Y.M.,Burtseva, A.D.,Mitkevich, O.V.,Baymukhametov, T.N.,Popov, V.O.,Boyko, K.M.,Kushnirov, V.V. Cryo-EM structure of ex vivo Sup35 yeast prion and the factors defining prion phenotype Nat Commun, 2026 Cited by DOI: 10.1038/s41467-026-77823-3 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.7 Å)

Structure validation