21BQ

Cryo-EM structure of ex vivo Sup35 prion fibrils from yeast carrying "strong" [PSI+] variant

Summary for 21BQ

• Entry DOI: 10.2210/pdb21bq/pdb
• EMDB information: 67558
• Descriptor: Amyloid of yeast prion Sup35 (1 entity in total)
• Functional Keywords: amyloid, prion, yeast, in vivo, natural, protein fibril
• Biological source: Saccharomyces cerevisiae
• Total number of polymer chains: 5
• Total formula weight: 89977.19

Authors

Chesnokov, Y.M.,Burtseva, A.D.,Dergalev, A.A.,Baimukhametov, T.N.,Kushnirov, V.V.,Popov, V.O.,Boyko, K.M. (deposition date: 2025-12-06, release date: 2026-07-22)

• Primary citation: Dergalev, A.A.,Chesnokov, Y.M.,Burtseva, A.D.,Kushnirov, V.V.,Boyko, K.M.,Popov, V.O.; CryoEM structure of ex vivo extracted Sup35 prion fibrils provides insights into [PSI+] prion phenotype determination and stability; To Be Published,

Experimental method

ELECTRON MICROSCOPY (2.7 Å)