1ZMD

Crystal Structure of Human dihydrolipoamide dehydrogenase complexed to NADH

1ZMD の概要

• エントリーDOI: 10.2210/pdb1zmd/pdb
• 関連するPDBエントリー: 1ZMC
• 分子名称: Dihydrolipoyl dehydrogenase, SULFATE ION, FLAVIN-ADENINE DINUCLEOTIDE, ... (5 entities in total)
• 機能のキーワード: e3, lipoamide dehydrogenase, pyruvate dehydrogenase, alpha-ketoglutarate dehydrogenase, branched-chain alpha-ketoacid dehydrogenase, glycine decarboxylase, glycine cleavage, oxidoreductase
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Mitochondrion matrix: P09622
• タンパク質・核酸の鎖数: 8
• 化学式量合計: 416253.13

構造登録者

Brautigam, C.A.,Chuang, J.L.,Tomchick, D.R.,Machius, M.,Chuang, D.T. (登録日: 2005-05-10, 公開日: 2005-06-28, 最終更新日: 2023-08-23)

• 主引用文献: Brautigam, C.A.,Chuang, J.L.,Tomchick, D.R.,Machius, M.,Chuang, D.T.; Crystal Structure of Human Dihydrolipoamide Dehydrogenase: NAD+/NADH Binding and the Structural Basis of Disease-causing Mutations; J.Mol.Biol., 350:543-552, 2005; PubMed: 15946682; DOI: 10.1016/j.jmb.2005.05.014

実験手法

X-RAY DIFFRACTION (2.08 Å)