1ZMC

Crystal Structure of Human dihydrolipoamide dehydrogenase complexed to NAD+

Summary for 1ZMC

Entry DOI	10.2210/pdb1zmc/pdb
Related	1ZMD
Descriptor	Dihydrolipoyl dehydrogenase, mitochondrial, SULFATE ION, FLAVIN-ADENINE DINUCLEOTIDE, ... (5 entities in total)
Functional Keywords	e3, lipoamide dehydrogenase, pyruvate dehydrogenase, alpha-ketoglutarate dehydrogenase, branched-chain alpha-ketoacid dehydrogenase, glycine decarboxylase, glycine cleavage, oxidoreductase
Biological source	Homo sapiens (Human)
Total number of polymer chains	8
Total formula weight	416717.32
Authors	Brautigam, C.A.,Chuang, J.L.,Tomchick, D.R.,Machius, M.,Chuang, D.T. (deposition date: 2005-05-10, release date: 2005-06-28, Last modification date: 2023-08-23)
Primary citation	Brautigam, C.A.,Chuang, J.L.,Tomchick, D.R.,Machius, M.,Chuang, D.T. Crystal Structure of Human Dihydrolipoamide Dehydrogenase: NAD(+)/NADH Binding and the Structural Basis of Disease-causing Mutations J.Mol.Biol., 350:543-552, 2005 Cited by PubMed: 15946682 DOI: 10.1016/j.jmb.2005.05.014 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.53 Å)

Structure validation