1ZLY
The structure of human glycinamide ribonucleotide transformylase in complex with alpha,beta-N-(hydroxyacetyl)-D-ribofuranosylamine and 10-formyl-5,8,dideazafolate
Summary for 1ZLY
Entry DOI | 10.2210/pdb1zly/pdb |
Related | 1MEJ 1MEN 1MEO 1NJS 1ZLX |
Descriptor | Phosphoribosylglycinamide formyltransferase, 5-O-phosphono-beta-D-ribofuranosylamine, 4-[(4-{[(2-AMINO-4-OXO-3,4-DIHYDROQUINAZOLIN-6-YL)METHYL]AMINO}BENZOYL)AMINO]BUTANOIC ACID, ... (4 entities in total) |
Functional Keywords | purine biosynthesis, transferase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 22474.60 |
Authors | Dahms, T.E.S.,Sainz, G.,Giroux, E.L.,Caperelli, C.A.,Smith, J.L. (deposition date: 2005-05-09, release date: 2005-08-23, Last modification date: 2023-08-23) |
Primary citation | Dahms, T.E.,Sainz, G.,Giroux, E.L.,Caperelli, C.A.,Smith, J.L. The apo and ternary complex structures of a chemotherapeutic target: human glycinamide ribonucleotide transformylase. Biochemistry, 44:9841-9850, 2005 Cited by PubMed: 16026156DOI: 10.1021/bi050307g PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.07 Å) |
Structure validation
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