X-ray Structure of a Kaposi's sarcoma herpesvirus LANA peptide bound to the nucleosomal core

Summary for 1ZLA

Related1aoi 1f66 1kx3 1kx4 1kx5
DescriptorPalindromic 146bp Human alpha-Satellite DNA fragment, histone H3, Histone H4, ... (7 entities in total)
Functional Keywordslatency associated nuclear antigen (lana), kaposi's sarcoma herpes virus (kshv), nucleosome core particle, chromatin, protein/protein interaction, protein binding-virus-dna complex, protein binding/virus/dna
Biological sourceHomo sapiens (human)
Cellular locationNucleus P62799
Total number of polymer chains11
Total molecular weight201529.63
Chodaparambil, J.V.,Barbera, A.J.,Kaye, K.M.,Luger, K. (deposition date: 2005-05-05, release date: 2006-02-28, Last modification date: 2011-07-13)
Primary citation
Barbera, A.J.,Chodaparambil, J.V.,Kelley-Clarke, B.,Joukov, V.,Walter, J.C.,Luger, K.,Kaye, K.M.
The nucleosomal surface as a docking station for Kaposi's sarcoma herpesvirus LANA.
Science, 311:856-861, 2006
PubMed: 16469929 (PDB entries with the same primary citation)
DOI: 10.1126/science.1120541
MImport into Mendeley
Experimental method
NMR Information

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.271221.6%6.1%1.2%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution