1ZLA

X-ray Structure of a Kaposi's sarcoma herpesvirus LANA peptide bound to the nucleosomal core

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	I, J	Palindromic 146bp Human alpha-Satellite DNA fragment	polymer	146	45054.8	2		Homo sapiens (human)
2	A, E	histone H3	polymer	135	15341.0	2	GenBank (288992) Pfam (PF00125) UniProt (by SIFTS) (P84233) In PDB	Xenopus laevis (African clawed frog)
3	B, F	Histone H4	polymer	102	11263.2	2	UniProt (P62799) Pfam (PF15511) In PDB	Xenopus laevis (African clawed frog)
4	C, G	Xenopus laevis-like histone H2A	polymer	129	14181.4	2	GenBank (30268540) Pfam (PF00125) Pfam (PF16211) UniProt (by SIFTS) (P06897) In PDB	Expression vector pET3-H2A
5	D, H	histone H2B	polymer	125	13794.0	2	GenBank (296216) Pfam (PF00125) UniProt (by SIFTS) (P02281) In PDB	Xenopus laevis (African clawed frog)
6	K	latent nuclear antigen	polymer	22	2260.6	1	GenBank (5669894) UniProt (by SIFTS) (Q9DUM3) In PDB
7		water	water		18.0	66	Chemie (HOH)

Sequence modifications

A, E: 401 - 535 (GenBank: 288992)

PDB	External Database	Details
Ala 511	Gly 112	engineered mutation
His 518	Thr 119	engineered mutation

C, G: 801 - 929 (GenBank: 30268540)

PDB	External Database	Details
Trp 869	Ala 70	engineered mutation
Glu 870	Ala 71	engineered mutation
Thr 926	Ala 127	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	11
	Total formula weight	201529.6
All*	Total formula weight	201529.6

*Water molecules are not included.