1YV6

X-ray structure of M23L onconase at 298K

Summary for 1YV6

Entry DOI	10.2210/pdb1yv6/pdb
Related	1YV4 1YV7
Descriptor	P-30 protein, SULFATE ION (3 entities in total)
Functional Keywords	small conformational changes, onconase thermal stability, ribonucleases, antitumor action, dynamics, hydrolase
Biological source	Rana pipiens (northern leopard frog)
Total number of polymer chains	1
Total formula weight	11923.67
Authors	Merlino, A.,Mazzarella, L.,Carannante, A.,Di Fiore, A.,Di Donato, A.,Notomista, E.,Sica, F. (deposition date: 2005-02-15, release date: 2005-03-01, Last modification date: 2021-11-10)
Primary citation	Merlino, A.,Mazzarella, L.,Carannante, A.,Di Fiore, A.,Di Donato, A.,Notomista, E.,Sica, F. The Importance of Dynamic Effects on the Enzyme Activity: X-RAY STRUCTURE AND MOLECULAR DYNAMICS OF ONCONASE MUTANTS J.Biol.Chem., 280:17953-17960, 2005 Cited by PubMed: 15728177 DOI: 10.1074/jbc.M501339200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.78 Å)

Structure validation