1YPJ
Thrombin Inhibitor Complex
Summary for 1YPJ
| Entry DOI | 10.2210/pdb1ypj/pdb |
| Related | 1Y3X 1YP9 1YPE 1YPG |
| Descriptor | Thrombin light chain, Thrombin heavy chain, Hirudin, ... (5 entities in total) |
| Functional Keywords | thrombin, inhibitor complex, barrel, 6 stranded beta-sheet, blood clotting-hydrolase inhibitor complex, blood clotting/hydrolase inhibitor |
| Biological source | Homo sapiens (human) More |
| Cellular location | Secreted, extracellular space: P00734 P00734 Secreted: P28504 |
| Total number of polymer chains | 3 |
| Total formula weight | 34594.64 |
| Authors | Fokkens, J.,Obst-Sander, U.,Heine, A.,Diederich, F.,Klebe, G. (deposition date: 2005-01-31, release date: 2006-01-17, Last modification date: 2017-10-11) |
| Primary citation | Fokkens, J.,Klebe, G. A simple protocol to estimate differences in protein binding affinity for enantiomers without prior resolution of racemates Angew.Chem.Int.Ed.Engl., 45:985-989, 2006 Cited by PubMed: 16374786DOI: 10.1002/anie.200502302 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.78 Å) |
Structure validation
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