1YND

Structure of human cyclophilin A in complex with the novel immunosuppressant sanglifehrin A at 1.6A resolution

Summary for 1YND

Entry DOI	10.2210/pdb1ynd/pdb
Related	1NMK
Descriptor	Peptidyl-prolyl cis-trans isomerase A, SANGLIFEHRIN A (3 entities in total)
Functional Keywords	beta sandwich, cyclophilin-ligand complex, cyclosporin, isomerase, rotamase
Biological source	Homo sapiens (human)
Cellular location	Cytoplasm: P62937
Total number of polymer chains	2
Total formula weight	38253.79
Authors	Kallen, J.,Sedrani, R.,Zenke, G.,Wagner, J. (deposition date: 2005-01-24, release date: 2005-04-05, Last modification date: 2023-08-23)
Primary citation	Kallen, J.,Sedrani, R.,Zenke, G.,Wagner, J. Structure of human cyclophilin A in complex with the novel immunosuppressant sanglifehrin A at 1.6 A resolution. J.Biol.Chem., 280:21965-21971, 2005 Cited by PubMed: 15772070 DOI: 10.1074/jbc.M501623200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.6 Å)

Structure validation