1YND

Structure of human cyclophilin A in complex with the novel immunosuppressant sanglifehrin A at 1.6A resolution

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Peptidyl-prolyl cis-trans isomerase A	polymer	165	18036.5	2	UniProt (P62937) Pfam (PF00160)	Homo sapiens (human)	PPIase, Rotamase, Cyclophilin A, Cyclosporin A-binding protein
2	C, D (A, B)	SANGLIFEHRIN A	non-polymer		1090.4	2	Chemie (SFA)
3	E, F (A, B)	water	water		18.0	362	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	36073.0
Non-Polymers*	Number of molecules	2
	Total formula weight	2180.8
All*	Total formula weight	38253.8

*Water molecules are not included.