1YGR
Crystal structure of the tandem phosphatase domain of RPTP CD45
Summary for 1YGR
Entry DOI | 10.2210/pdb1ygr/pdb |
Descriptor | CD45 Protein Tyrosine Phosphatase, T-cell Receptor CD3 zeta ITAM-1 (2 entities in total) |
Functional Keywords | protein tyrosine phosphatase, rptp, cd45, lca, lymphocyte activation, cd3 zeta, itam, hydrolase |
Biological source | Homo sapiens (human) More |
Cellular location | Membrane ; Single-pass type I membrane protein : P08575 P20963 |
Total number of polymer chains | 4 |
Total formula weight | 144782.87 |
Authors | Nam, H.J.,Poy, F.,Saito, H.,Frederick, C.A. (deposition date: 2005-01-05, release date: 2005-02-22, Last modification date: 2021-10-20) |
Primary citation | Nam, H.J.,Poy, F.,Saito, H.,Frederick, C.A. Structural basis for the function and regulation of the receptor protein tyrosine phosphatase CD45. J.Exp.Med., 201:441-452, 2005 Cited by PubMed: 15684325DOI: 10.1084/jem.20041890 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.9 Å) |
Structure validation
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