1YF8

Crystal structure of Himalayan mistletoe RIP reveals the presence of a natural inhibitor and a new functionally active sugar-binding site

Summary for 1YF8

• Entry DOI: 10.2210/pdb1yf8/pdb
• Related PRD ID: PRD_900004
• Descriptor: Beta-galactoside-specific lectin 4, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (10 entities in total)
• Functional Keywords: himalayan mistletoe, ribosome inactivating protein, viscum album, natural inhibitor, sugar-binding site, hydrolase
• Biological source: Viscum album (European mistletoe); More
• Total number of polymer chains: 2
• Total formula weight: 57279.37

Authors

Mishra, V.,Bilgrami, S.,Sharma, R.S.,Kaur, P.,Yadav, S.,Betzel, C.,Babu, C.R.,Singh, T.P. (deposition date: 2004-12-31, release date: 2005-03-08, Last modification date: 2023-10-25)

• Primary citation: Mishra, V.,Bilgrami, S.,Sharma, R.S.,Kaur, P.,Yadav, S.,Krauspenhaar, R.,Betzel, C.,Voelter, W.,Babu, C.R.,Singh, T.P.; Crystal structure of himalayan mistletoe ribosome-inactivating protein reveals the presence of a natural inhibitor and a new functionally active sugar-binding site.; J.Biol.Chem., 280:20712-20721, 2005; PubMed: 15774467; DOI: 10.1074/jbc.M500735200

Experimental method

X-RAY DIFFRACTION (2.8 Å)