1Y5V

tRNA-Guanine Transglycosylase (TGT) in complex with 6-Amino-4-(2-phenylethyl)-1,7-dihydro-8H-imidazo[4,5-g]quinazolin-8-one

1Y5V の概要

• エントリーDOI: 10.2210/pdb1y5v/pdb
• 関連するPDBエントリー: 1Q4W 1Q63 1Q65 1Q66 1R5Y 1S38 1Y5W 1Y5X
• 分子名称: Queuine tRNA-ribosyltransferase, ZINC ION, 6-AMINO-4-(2-PHENYLETHYL)-1,7-DIHYDRO-8H-IMIDAZO[4,5-G]QUINAZOLIN-8-ONE, ... (5 entities in total)
• 機能のキーワード: transferase
• 由来する生物種: Zymomonas mobilis
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 43349.44

構造登録者

Stengl, B.,Meyer, E.A.,Heine, A.,Brenk, R.,Diederich, F.,Klebe, G. (登録日: 2004-12-03, 公開日: 2005-12-13, 最終更新日: 2023-10-25)

• 主引用文献: Stengl, B.,Meyer, E.A.,Heine, A.,Brenk, R.,Diederich, F.,Klebe, G.; Crystal structures of tRNA-guanine transglycosylase (TGT) in complex with novel and potent inhibitors unravel pronounced induced-fit adaptations and suggest dimer formation upon substrate binding; J.Mol.Biol., 370:492-511, 2007; PubMed: 17524419; DOI: 10.1016/j.jmb.2007.04.008

実験手法

X-RAY DIFFRACTION (1.58 Å)