1Y5R
The crystal structure of murine 11b-hydroxysteroid dehydrogenase complexed with corticosterone
Summary for 1Y5R
Entry DOI | 10.2210/pdb1y5r/pdb |
Related | 1Y5M |
Descriptor | Corticosteroid 11-beta-dehydrogenase, isozyme 1, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, CORTICOSTERONE (3 entities in total) |
Functional Keywords | corticosterone bound, oxidoreductase |
Biological source | Mus musculus (house mouse) |
Cellular location | Endoplasmic reticulum membrane; Single-pass type II membrane protein: P50172 |
Total number of polymer chains | 2 |
Total formula weight | 63355.12 |
Authors | Zhang, J.,Osslund, T.D.,Plant, M.H.,Clogston, C.L.,Nybo, R.E.,Xiong, F.,Delaney, J.M.,Jordan, S. (deposition date: 2004-12-02, release date: 2005-05-17, Last modification date: 2024-02-14) |
Primary citation | Zhang, J.,Osslund, T.D.,Plant, M.H.,Clogston, C.L.,Nybo, R.E.,Xiong, F.,Delaney, J.M.,Jordan, S. Crystal Structure of Murine 11-Hydroxysteroid Dehydrogenase 1: An Important Therapeutic Target for Diabetes Biochemistry, 44:6948-6957, 2005 Cited by PubMed: 15865440DOI: 10.1021/bi047599q PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3 Å) |
Structure validation
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