1Y2F

Crystal Structure of ZipA with an inhibitor

Summary for 1Y2F

Related1Y2G
DescriptorCell division protein zipA, 4-{2-[4-(2-AMINOETHYL)PIPERAZIN-1-YL]PYRIDIN-4-YL}-N-(3-CHLORO-4-METHYLPHENYL)PYRIMIDIN-2-AMINE (3 entities in total)
Functional Keywordscell cycle
Biological sourceEscherichia coli
Cellular locationCell inner membrane; Single-pass type I membrane protein P77173
Total number of polymer chains1
Total molecular weight15957.61
Authors
Mosyak, L.,Rush, T.S. (deposition date: 2004-11-22, release date: 2005-03-01, Last modification date: 2011-07-13)
Primary citation
Rush, T.S.,Grant, J.A.,Mosyak, L.,Nicholls, A.
A shape-based 3-D scaffold hopping method and its application to a bacterial protein-protein interaction
J.Med.Chem., 48:1489-1495, 2005
PubMed: 15743191 (PDB entries with the same primary citation)
DOI: 10.1021/jm040163o
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2 Å)
NMR Information
?

Structure validation

ClashscoreRamachandran outliersSidechain outliers1908.5%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution