1XPM
Crystal Structure of Staphylococcus aureus HMG-COA Synthase with HMG-CoA and Acetoacetyl-COA and Acetylated Cysteine
Summary for 1XPM
Entry DOI | 10.2210/pdb1xpm/pdb |
Related | 1XPK 1XPL |
Descriptor | 3-hydroxy-3-methylglutaryl CoA synthase, SULFATE ION, 3-HYDROXY-3-METHYLGLUTARYL-COENZYME A, ... (5 entities in total) |
Functional Keywords | hmg-coa synthase, hmgs, coenzyme a, thiolase fold, condensing enzyme, cholesterol biosynthesis, transferase |
Biological source | Staphylococcus aureus subsp. aureus |
Total number of polymer chains | 4 |
Total formula weight | 185143.33 |
Authors | Theisen, M.J.,Misra, I.,Saadat, D.,Campobasso, N.,Miziorko, H.M.,Harrison, D.H.T. (deposition date: 2004-10-08, release date: 2004-11-02, Last modification date: 2023-08-23) |
Primary citation | Theisen, M.J.,Misra, I.,Saadat, D.,Campobasso, N.,Miziorko, H.M.,Harrison, D.H.T. 3-hydroxy-3-methylglutaryl-CoA synthase intermediate complex observed in "real-time" Proc.Natl.Acad.Sci.USA, 47:16442-16447, 2004 Cited by PubMed: 15498869DOI: 10.1073/pnas.0405809101 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.6 Å) |
Structure validation
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