1XPM
Crystal Structure of Staphylococcus aureus HMG-COA Synthase with HMG-CoA and Acetoacetyl-COA and Acetylated Cysteine
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D | 3-hydroxy-3-methylglutaryl CoA synthase | polymer | 396 | 44335.5 | 4 | UniProt (Q79ZY6) Pfam (PF01154) Pfam (PF08540) UniProt (by SIFTS) (A0A0H3K1U2) In PDB | Staphylococcus aureus subsp. aureus | |
2 | A, B, C, D | SULFATE ION | non-polymer | 96.1 | 8 | Chemie (SO4) | |||
3 | A, B, C, D | 3-HYDROXY-3-METHYLGLUTARYL-COENZYME A | non-polymer | 906.6 | 4 | Chemie (HMG) | |||
4 | A, B, C, D | ACETOACETYL-COENZYME A | non-polymer | 851.6 | 4 | Chemie (CAA) | |||
5 | water | water | 18.0 | 1083 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 388 (UniProt: Q79ZY6)
PDB | External Database | Details |
---|---|---|
Met 1 | - | initiating methionine |
Ala 2 | - | cloning artifact |
Scy 111 | Cys 111 | microheterogeneity |
Leu 389 | - | cloning artifact |
Glu 390 | - | cloning artifact |
His 391 | - | expression tag |
His 392 | - | expression tag |
His 393 | - | expression tag |
His 394 | - | expression tag |
His 395 | - | expression tag |
His 396 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 177341.9 | |
Non-Polymers* | Number of molecules | 16 |
Total formula weight | 7801.4 | |
All* | Total formula weight | 185143.3 |