1XLZ

Catalytic Domain Of Human Phosphodiesterase 4B In Complex With Filaminast

Summary for 1XLZ

Entry DOI	10.2210/pdb1xlz/pdb
Related	1XLX 1XM4 1XM6 1XMU 1XMY 1XN0 1XOM 1XON 1XOQ 1XOR 1XOS 1XOT 1XOZ 1XP0
Descriptor	cAMP-specific 3',5'-cyclic phosphodiesterase 4B, ZINC ION, MAGNESIUM ION, ... (5 entities in total)
Functional Keywords	pde4b, filaminast, hydrolase
Biological source	Homo sapiens (human)
Total number of polymer chains	2
Total formula weight	92378.99
Authors	Card, G.L.,England, B.P.,Suzuki, Y.,Fong, D.,Powell, B.,Lee, B.,Luu, C.,Tabrizizad, M.,Gillette, S.,Ibrahim, P.N.,Artis, D.R.,Bollag, G.,Milburn, M.V.,Kim, S.-H.,Schlessinger, J.,Zhang, K.Y.J. (deposition date: 2004-09-30, release date: 2004-12-14, Last modification date: 2011-07-13)
Primary citation	Card, G.L.,England, B.P.,Suzuki, Y.,Fong, D.,Powell, B.,Lee, B.,Luu, C.,Tabrizizad, M.,Gillette, S.,Ibrahim, P.N.,Artis, D.R.,Bollag, G.,Milburn, M.V.,Kim, S.-H.,Schlessinger, J.,Zhang, K.Y.J. Structural Basis for the Activity of Drugs that Inhibit Phosphodiesterases. STRUCTURE, 12:2233-2247, 2004 Cited by PubMed: 15576036 DOI: 10.1016/j.str.2004.10.004 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.06 Å)

Structure validation