1XJB
Crystal structure of human type 3 3alpha-hydroxysteroid dehydrogenase in complex with NADP(H), citrate and acetate molecules
Summary for 1XJB
Entry DOI | 10.2210/pdb1xjb/pdb |
Descriptor | Aldo-keto reductase family 1 member C2, ACETATE ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... (8 entities in total) |
Functional Keywords | human 3alphahds3; aldo-keto reductase; nadp; induce-fit mecanism, oxidoreductase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 2 |
Total formula weight | 76163.19 |
Authors | Couture, J.-F.,Pereira de Jesus-Tran, K.,Roy, A.-M.,Legrand, P.,Cantin, L.,Cote, P.-L.,Luu-The, V.,Labrie, F.,Breton, R. (deposition date: 2004-09-23, release date: 2005-06-21, Last modification date: 2023-08-23) |
Primary citation | Couture, J.-F.,Roy, A.-M.,Cantin, L.,Legrand, P.,Luu-The, V.,Labrie, F.,Breton, R. Comparison of crystal structures of human type 3 3alpha-hydroxysteroid dehydrogenase reveals an "induced-fit" mechanism and a conserved basic motif involved in the binding of androgen Protein Sci., 14:1485-1497, 2005 Cited by PubMed: 15929998DOI: 10.1110/ps.051353205 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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