1XHY

X-ray structure of the Y702F mutant of the GluR2 ligand-binding core (S1S2J) in complex with kainate at 1.85 A resolution

1XHY の概要

• エントリーDOI: 10.2210/pdb1xhy/pdb
• 関連するPDBエントリー: 1fw0
• 分子名称: Glutamate receptor, SULFATE ION, 3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE, ... (4 entities in total)
• 機能のキーワード: ionotropic glutamate receptor glur2, mutant, ligand-binding core, kainate complex, membrane protein
• 由来する生物種: Rattus norvegicus (Rat); 詳細
• 細胞内の位置: Cell membrane; Multi-pass membrane protein: P19491
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 29899.23

構造登録者

Frandsen, A.,Pickering, D.S.,Vestergaard, B.,Kasper, C.,Nielsen, B.B.,Greenwood, J.R.,Campiani, G.,Gajhede, M.,Schousboe, A.,Kastrup, J.S. (登録日: 2004-09-21, 公開日: 2005-03-22, 最終更新日: 2023-08-23)

• 主引用文献: Frandsen, A.,Pickering, D.S.,Vestergaard, B.,Kasper, C.,Nielsen, B.B.,Greenwood, J.R.,Campiani, G.,Fattorusso, C.,Gajhede, M.,Schousboe, A.,Kastrup, J.S.; Tyr702 Is an Important Determinant of Agonist Binding and Domain Closure of the Ligand-Binding Core of GluR2.; Mol.Pharmacol., 67:703-713, 2005; PubMed: 15591246; DOI: 10.1124/mol.104.002931

実験手法

X-RAY DIFFRACTION (1.85 Å)