1XG3

Crystal structure of the C123S 2-methylisocitrate lyase mutant from Escherichia coli in complex with the reaction product, Mg(II)-pyruvate and succinate

1XG3 の概要

• エントリーDOI: 10.2210/pdb1xg3/pdb
• 関連するPDBエントリー: 1oqf
• 分子名称: Probable methylisocitrate lyase, MAGNESIUM ION, PYRUVIC ACID, ... (5 entities in total)
• 機能のキーワード: 2-methylisocitrate lyase-product complex, succinate, pyruvate, isocitrate lyase superfamily, lyase
• 由来する生物種: Escherichia coli
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 128893.15

構造登録者

Liu, S.,Lu, Z.,Han, Y.,Melamud, E.,Dunaway-Mariano, D.,Herzberg, O. (登録日: 2004-09-16, 公開日: 2005-03-01, 最終更新日: 2024-04-03)

• 主引用文献: Liu, S.,Lu, Z.,Han, Y.,Melamud, E.,Dunaway-Mariano, D.,Herzberg, O.; Crystal Structures of 2-Methylisocitrate Lyase in Complex with Product and with Isocitrate Inhibitor Provide Insight into Lyase Substrate Specificity, Catalysis and Evolution; Biochemistry, 44:2949-2962, 2005; PubMed: 15723538; DOI: 10.1021/bi0479712

実験手法

X-RAY DIFFRACTION (1.9 Å)