1WUR

Structure of GTP cyclohydrolase I Complexed with 8-oxo-dGTP

Summary for 1WUR

• Entry DOI: 10.2210/pdb1wur/pdb
• Related: 1WUQ
• Descriptor: GTP cyclohydrolase I, ZINC ION, 8-OXO-2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ... (4 entities in total)
• Functional Keywords: beta barrel, protein-inhibitor complex, hydrolase, pteridine, tetrahydrobiopterin, structural genomics, nppsfa, national project on protein structural and functional analyses, riken structural genomics/proteomics initiative, rsgi
• Biological source: Thermus thermophilus
• Total number of polymer chains: 5
• Total formula weight: 125799.60

Authors

Tanaka, Y.,Nakagawa, N.,Masui, R.,Yokoyama, S.,Kuramitsu, S.,RIKEN Structural Genomics/Proteomics Initiative (RSGI) (deposition date: 2004-12-08, release date: 2005-07-19, Last modification date: 2024-03-13)

• Primary citation: Tanaka, Y.,Nakagawa, N.,Kuramitsu, S.,Yokoyama, S.,Masui, R.; Novel reaction mechanism of GTP cyclohydrolase I. High-resolution X-ray crystallography of Thermus thermophilus HB8 enzyme complexed with a transition state analogue, the 8-oxoguanine derivative; J.Biochem.(Tokyo), 138:263-275, 2005; PubMed: 16169877; DOI: 10.1093/jb/mvi120

Experimental method

X-RAY DIFFRACTION (1.82 Å)