1WDC

SCALLOP MYOSIN REGULATORY DOMAIN

Summary for 1WDC

Entry DOI	10.2210/pdb1wdc/pdb
Descriptor	SCALLOP MYOSIN, MAGNESIUM ION, CALCIUM ION, ... (6 entities in total)
Functional Keywords	myosin, calcium binding protein, muscle protein
Biological source	Argopecten irradians More
Cellular location	Cytoplasm, myofibril: P24733
Total number of polymer chains	3
Total formula weight	43258.50
Authors	Houdusse, A.,Cohen, C. (deposition date: 1996-01-19, release date: 1996-07-11, Last modification date: 2024-02-14)
Primary citation	Houdusse, A.,Cohen, C. Structure of the regulatory domain of scallop myosin at 2 A resolution: implications for regulation. Structure, 4:21-32, 1996 Cited by PubMed Abstract: In contrast to the myosins of vertebrate skeletal muscle, molluscan myosins are regulated molecules whose enzymatic activity is switched on by the direct binding of Ca2+. The head portion (S1) of the molecule consists of a motor domain and a regulatory domain (RD) containing a 'regulatory' and an 'essential' light chain (RLC and ELC, respectively). The structures of scallop myosin RD with bound Ca2+, as well as the S1 fragment of chicken skeletal muscle myosin, have been determined previously to 2.8 A resolution. PubMed: 8805510 DOI: 10.1016/S0969-2126(96)00154-2 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation