1W88

The crystal structure of pyruvate dehydrogenase E1(D180N,E183Q) bound to the peripheral subunit binding domain of E2

1W88 の概要

• エントリーDOI: 10.2210/pdb1w88/pdb
• 関連するPDBエントリー: 1B5S 1EBD 1LAB 1LAC 1W3D 1W4E 1W4F 1W4G 1W4H 1W85 2PDD 2PDE
• 分子名称: PYRUVATE DEHYDROGENASE E1 COMPONENT, ALPHA SUBUNIT, PYRUVATE DEHYDROGENASE E1 COMPONENT, BETA SUBUNIT, DIHYDROLIPOYLLYSINE-RESIDUE ACETYLTRANSFERASE COMPONENT OF PYRUVATE, ... (6 entities in total)
• 機能のキーワード: pyruvate dehydrogenase, dihydrolipoyl, acetyl transferase, multienzyme complex, oxidoreductase, transferase, catalysis, slinky
• 由来する生物種: GEOBACILLUS STEAROTHERMOPHILUS; 詳細
• タンパク質・核酸の鎖数: 10
• 化学式量合計: 319320.48

構造登録者

Frank, R.A.W.,Pratap, J.V.,Pei, X.Y.,Perham, R.N.,Luisi, B.F. (登録日: 2004-09-16, 公開日: 2004-11-02, 最終更新日: 2023-12-13)

• 主引用文献: Frank, R.A.W.,Titman, C.M.,Pratap, J.V.,Luisi, B.F.,Perham, R.N.; A Molecular Switch and Proton-Wire Synchronize the Active Sites in Thiamine-Dependent Enzymes; Science, 306:872-, 2004; PubMed: 15514159; DOI: 10.1126/SCIENCE.1101030

実験手法

X-RAY DIFFRACTION (2.3 Å)