1W72
Crystal structure of HLA-A1:MAGE-A1 in complex with Fab-Hyb3
Summary for 1W72
Entry DOI | 10.2210/pdb1w72/pdb |
Related | 1AO7 1BD2 1FO0 1G6R 1MWA 1OGA 2CKB |
Descriptor | HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, BETA-2-MICROGLOBULIN, MELANOMA-ASSOCIATED ANTIGEN 1, ... (7 entities in total) |
Functional Keywords | immune system, hla/fab fragment, human leucocyte antigen, peptide-specific fab, tcr-like binding, mhc-i |
Biological source | HOMO SAPIENS (HUMAN) More |
Cellular location | Membrane; Single-pass type I membrane protein: P30443 Secreted: P61769 Cytoplasm: P43355 |
Total number of polymer chains | 10 |
Total formula weight | 182094.00 |
Authors | Hulsmeyer, M.,Chames, P.,Hillig, R.C.,Stanfield, R.L.,Held, G.,Coulie, P.G.,Alings, C.,Wille, G.,Saenger, W.,Uchanska-Ziegler, B.,Hoogenboom, H.R.,Ziegler, A. (deposition date: 2004-08-27, release date: 2004-11-09, Last modification date: 2023-12-13) |
Primary citation | Hulsmeyer, M.,Chames, P.,Hillig, R.C.,Stanfield, R.L.,Held, G.,Coulie, P.G.,Alings, C.,Wille, G.,Saenger, W.,Uchanska-Ziegler, B.,Hoogenboom, H.R.,Ziegler, A. A Major Histocompatibility Complex.Peptide- Restricted Antibody and T Cell Receptor Molecules Recognize Their Target by Distinct Binding Modes: Crystal Structure of Human Leukocyte Antigen (Hla)-A1.Mage-A1 in Complex with Fab-Hyb3 J.Biol.Chem., 280:2972-, 2005 Cited by PubMed: 15537658DOI: 10.1074/JBC.M411323200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.15 Å) |
Structure validation
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