1W72
Crystal structure of HLA-A1:MAGE-A1 in complex with Fab-Hyb3
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D (A, D) | HLA CLASS I HISTOCOMPATIBILITY ANTIGEN | polymer | 274 | 31637.0 | 2 | UniProt (P30443) Pfam (PF00129) Pfam (PF07654) UniProt (by SIFTS) (P04439) | HOMO SAPIENS (HUMAN) | HUMAN LYMPHOCYTE ANTIGEN HLA-A1, A-1 ALPHA CHAIN PRECURSOR MHC CLASS I ANTIGEN A*1 |
| 2 | B, E (B, E) | BETA-2-MICROGLOBULIN | polymer | 100 | 11879.4 | 2 | UniProt (P61769) Pfam (PF07654) | HOMO SAPIENS (HUMAN) | HDCMA22P |
| 3 | C, F (C, F) | MELANOMA-ASSOCIATED ANTIGEN 1 | polymer | 9 | 977.0 | 2 | UniProt (P43355) | HOMO SAPIENS | MAGE-A1, MAGE-1 ANTIGEN, ANTIGEN MZ2-E |
| 4 | G, H (H, I) | HYB3 HEAVY CHAIN | polymer | 223 | 23845.7 | 2 | HOMO SAPIENS (HUMAN) | ||
| 5 | I, J (L, M) | HYB3 LIGHT CHAIN | polymer | 210 | 22523.9 | 2 | HOMO SAPIENS (HUMAN) | ||
| 6 | K, L, M, N (A, I, M) | GLYCEROL | non-polymer | 92.1 | 4 | Chemie (GOL) | |||
| 7 | O, P, Q, R, S... (A, B, C, D, E...) | water | water | 18.0 | 653 | Chemie (HOH) |
Sequence modifications
B, E: 1 - 99 (UniProt: P61769)
| PDB | External Database | Details |
|---|---|---|
| Met 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 10 |
| Total formula weight | 181725.6 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 368.4 | |
| All* | Total formula weight | 182094.0 |
