1W3Y

Crystal structure of S. pneumoniae hyaluronate lyase in complex with palmitoyl-vitamin C

Summary for 1W3Y

Entry DOI	10.2210/pdb1w3y/pdb
Related	1C82 1EGU 1F9G 1LOH 1LXK 1N7N 1N7O 1N7P 1N7Q 1N7R 1OJM 1OJN 1OJO 1OJP
Descriptor	HYALURONATE LYASE, (2E,4R,5S)-2,3,4,5-TETRAHYDROXY-6-(PALMITOYLOXY)HEX-2-ENOIC ACID, Xylitol, ... (5 entities in total)
Functional Keywords	(alfa5/alfa5) barrel, lyase, peptidoglycan-anchor
Biological source	STREPTOCOCCUS PNEUMONIAE
Total number of polymer chains	1
Total formula weight	84779.09
Authors	Rigden, D.J.,Jedrzejas, M.J. (deposition date: 2004-07-21, release date: 2004-08-26, Last modification date: 2020-07-29)
Primary citation	Botzki, A.,Rigden, D.J.,Braun, S.,Nukui, M.,Salmen, S.,Hoechstetter, J.,Bernhardt, G.,Dove, S.,Jedrzejas, M.J.,Buschauer, A. L-Ascorbic Acid 6-Hexadecanoate, a Potent Hyaluronidase Inhibitor: X-Ray Structure and Molecular Modeling of Enzyme-Inhibitor Complexes J.Biol.Chem., 279:45990-, 2004 Cited by PubMed: 15322107 DOI: 10.1074/JBC.M406146200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.65 Å)

Structure validation