1W2G
Crystal Structure Of Mycobacterium Tuberculosis Thymidylate Kinase Complexed With Deoxythymidine (dT) (2.1 A Resolution)
Summary for 1W2G
| Entry DOI | 10.2210/pdb1w2g/pdb |
| Related | 1G3U 1GSI 1GTV 1MRN 1MRS 1N5I 1N5J 1N5K 1N5L 1W2H |
| Descriptor | THYMIDYLATE KINASE TMK, ACETATE ION, THYMIDINE, ... (4 entities in total) |
| Functional Keywords | mycobacterium tuberculosis, thymidylate kinase, azt, inhibition mechanism, transferase |
| Biological source | MYCOBACTERIUM TUBERCULOSIS |
| Total number of polymer chains | 2 |
| Total formula weight | 45986.64 |
| Authors | Fioravanti, E.,Adam, V.,Munier-Lehmann, H.,Bourgeois, D. (deposition date: 2004-07-06, release date: 2005-01-12, Last modification date: 2023-12-13) |
| Primary citation | Fioravanti, E.,Adam, V.,Munier-Lehmann, H.,Bourgeois, D. The Crystal Structure of Mycobacterium Tuberculosis Thymidylate Kinase in Complex with 3'-Azidodeoxythymidine Monophosphate Suggests a Mechanism for Competitive Inhibition Biochemistry, 44:130-, 2005 Cited by PubMed: 15628853DOI: 10.1021/BI0484163 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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