1V84

Crystal structure of human GlcAT-P in complex with N-acetyllactosamine, Udp, and Mn2+

1V84 の概要

• エントリーDOI: 10.2210/pdb1v84/pdb
• 関連するPDBエントリー: 1V82 1V83
• 関連するBIRD辞書のPRD_ID: PRD_900019
• 分子名称: Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total)
• 機能のキーワード: transferase, glycoprotein, glycocyltransferase, hnk-1 epitope
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Golgi apparatus membrane; Single-pass type II membrane protein: Q9P2W7
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 59911.80

構造登録者

Kakuda, S.,Shiba, T.,Ishiguro, M.,Tagawa, H.,Oka, S.,Kajihara, Y.,Kawasaki, T.,Wakatsuki, S.,Kato, R. (登録日: 2003-12-27, 公開日: 2004-05-25, 最終更新日: 2023-10-25)

• 主引用文献: Kakuda, S.,Shiba, T.,Ishiguro, M.,Tagawa, H.,Oka, S.,Kajihara, Y.,Kawasaki, T.,Wakatsuki, S.,Kato, R.; Structural Basis for Acceptor Substrate Recognition of a Human Glucuronyltransferase, GlcAT-P, an Enzyme Critical in the Biosynthesis of the Carbohydrate Epitope HNK-1; J.Biol.Chem., 279:22693-22703, 2004; PubMed: 14993226; DOI: 10.1074/jbc.M400622200

実験手法

X-RAY DIFFRACTION (1.82 Å)