1V2H

Crystal structure of human PNP complexed with guanine

Summary for 1V2H

Entry DOI	10.2210/pdb1v2h/pdb
Related	1M73 1PF7
Descriptor	Purine nucleoside phosphorylase, SULFATE ION, GUANINE, ... (4 entities in total)
Functional Keywords	purine nucleoside phosphorylase, drug design, synchrotron, guanine, transferase
Biological source	Homo sapiens (human)
Cellular location	Cytoplasm, cytoskeleton (By similarity): P00491
Total number of polymer chains	1
Total formula weight	32589.06
Authors	De Azevedo Jr., W.F.,Canduri, F.,Pereira, J.H.,Dos Santos, D.M.,Bertacine Dias, M.V.,Silva, R.G.,Palma, M.S.,Basso, L.A.,Santos, D.S. (deposition date: 2003-10-16, release date: 2004-01-13, Last modification date: 2023-10-25)
Primary citation	de Azevedo Jr., W.F.,Canduri, F.,dos Santos, D.M.,Pereira, J.H.,Bertacine Dias, M.V.,Silva, R.G.,Mendes, M.A.,Basso, L.A.,Palma, M.S.,Santos, D.S. Crystal structure of human PNP complexed with guanine. Biochem.Biophys.Res.Commun., 312:767-772, 2003 Cited by PubMed: 14680831 DOI: 10.1016/j.bbrc.2003.10.190 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.7 Å)

Structure validation