1V0K

Xylanase Xyn10A from Streptomyces lividans in complex with xylobio-deoxynojirimycin at pH 5.8

Summary for 1V0K

Entry DOI	10.2210/pdb1v0k/pdb
Related	1E0V 1E0W 1E0X 1KNL 1KNM 1MC9 1OD8 1V0L 1V0M 1V0N 1XAS
Descriptor	ENDO-1,4-BETA-XYLANASE A, beta-D-xylopyranose, PIPERIDINE-3,4,5-TRIOL, ... (4 entities in total)
Functional Keywords	glycoside hydrolase family 10, xylanase, xylan degradation, deoxynojirimycin, hydrolase
Biological source	STREPTOMYCES LIVIDANS
Cellular location	Secreted: P26514
Total number of polymer chains	1
Total formula weight	34412.73
Authors	Gloster, T.M.,Williams, S.J.,Roberts, S.,Tarling, C.A.,Wicki S, J.,Withers, G.,Davies, G.J. (deposition date: 2004-03-31, release date: 2004-08-16, Last modification date: 2023-12-13)
Primary citation	Gloster, T.M.,Williams, S.J.,Roberts, S.,Tarling, C.A.,Wicki, J.,Withers, S.G.,Davies, G.J. Atomic Resolution Analyses of the Binding of Xylobiose-Derived Deoxynojirimycin and Isofagomine to Xylanase Xyn10A Chem.Commun.(Camb.), 16:1794-, 2004 Cited by PubMed Abstract: The atomic resolution structures of xylobiose-derived isofagomine and xylobiose-derived deoxynojirimycin in complex with the xylanase Xyn10A from Streptomyces lividans reveal undistorted (4)C(1) chair conformed sugars and, in the case of the deoxynojirimycin analogue, suggest unusual pK(a) changes of the enzyme's catalytic machinery upon binding. PubMed: 15306887 DOI: 10.1039/B405152A PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.03 Å)

Structure validation