1UUO

Rat dihydroorotate dehydrogenase (DHOD)in complex with brequinar

1UUO の概要

• エントリーDOI: 10.2210/pdb1uuo/pdb
• 関連するPDBエントリー: 1UUM
• 分子名称: DIHYDROOROTATE DEHYDROGENASE, 6-FLUORO-2-(2'-FLUORO-1,1'-BIPHENYL-4-YL)-3-METHYLQUINOLINE-4-CARBOXYLIC ACID, FLAVIN MONONUCLEOTIDE, ... (7 entities in total)
• 機能のキーワード: dihydroorotate dehydrogenase, brequinar, atovaquone, nucleotide metabolism, oxidoreductase
• 由来する生物種: RATTUS RATTUS (BLACK RAT, ROOF RAT)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 41410.37

構造登録者

Hansen, M.,Le Nours, J.,Johansson, E.,Antal, T.,Ullrich, A.,Loffler, M.,Larsen, S. (登録日: 2004-01-08, 公開日: 2004-04-01, 最終更新日: 2024-05-08)

• 主引用文献: Hansen, M.,Le Nours, J.,Johansson, E.,Antal, T.,Ullrich, A.,Loffler, M.,Larsen, S.; Inhibitor Binding in a Class 2 Dihydroorotate Dehydrogenase Causes Variations in the Membrane-Associated N-Terminal Domain; Protein Sci., 13:1031-, 2004; PubMed: 15044733; DOI: 10.1110/PS.03533004

実験手法

X-RAY DIFFRACTION (2.44 Å)