1UUO
Rat dihydroorotate dehydrogenase (DHOD)in complex with brequinar
Summary for 1UUO
Entry DOI | 10.2210/pdb1uuo/pdb |
Related | 1UUM |
Descriptor | DIHYDROOROTATE DEHYDROGENASE, 6-FLUORO-2-(2'-FLUORO-1,1'-BIPHENYL-4-YL)-3-METHYLQUINOLINE-4-CARBOXYLIC ACID, FLAVIN MONONUCLEOTIDE, ... (7 entities in total) |
Functional Keywords | dihydroorotate dehydrogenase, brequinar, atovaquone, nucleotide metabolism, oxidoreductase |
Biological source | RATTUS RATTUS (BLACK RAT, ROOF RAT) |
Total number of polymer chains | 1 |
Total formula weight | 41410.37 |
Authors | Hansen, M.,Le Nours, J.,Johansson, E.,Antal, T.,Ullrich, A.,Loffler, M.,Larsen, S. (deposition date: 2004-01-08, release date: 2004-04-01, Last modification date: 2024-05-08) |
Primary citation | Hansen, M.,Le Nours, J.,Johansson, E.,Antal, T.,Ullrich, A.,Loffler, M.,Larsen, S. Inhibitor Binding in a Class 2 Dihydroorotate Dehydrogenase Causes Variations in the Membrane-Associated N-Terminal Domain Protein Sci., 13:1031-, 2004 Cited by PubMed: 15044733DOI: 10.1110/PS.03533004 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.44 Å) |
Structure validation
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