1UPU

STRUCTURE OF THE URACIL PHOSPHORIBOSYLTRANSFERASE, MUTANT C128V, BOUND TO PRODUCT URIDINE-1-MONOPHOSPHATE (UMP)

1UPU の概要

• エントリーDOI: 10.2210/pdb1upu/pdb
• 分子名称: URACIL PHOSPHORIBOSYLTRANSFERASE, PHOSPHATE ION, URIDINE-5'-MONOPHOSPHATE, ... (4 entities in total)
• 機能のキーワード: transferase, glycosyltransferase, phosphoribosyltransferase
• 由来する生物種: Toxoplasma gondii
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 103848.66

構造登録者

Schumacher, M.A.,Carter, D.,Scott, D.,Roos, D.,Ullman, B.,Brennan, R.G. (登録日: 1998-04-16, 公開日: 1999-05-11, 最終更新日: 2024-02-14)

• 主引用文献: Schumacher, M.A.,Carter, D.,Scott, D.M.,Roos, D.S.,Ullman, B.,Brennan, R.G.; Crystal structures of Toxoplasma gondii uracil phosphoribosyltransferase reveal the atomic basis of pyrimidine discrimination and prodrug binding.; EMBO J., 17:3219-3232, 1998; PubMed: 9628859; DOI: 10.1093/emboj/17.12.3219

実験手法

X-RAY DIFFRACTION (2.5 Å)