1UEA
MMP-3/TIMP-1 COMPLEX
Summary for 1UEA
Entry DOI | 10.2210/pdb1uea/pdb |
Descriptor | MATRIX METALLOPROTEINASE-3, TISSUE INHIBITOR OF METALLOPROTEINASE-1, ZINC ION, ... (5 entities in total) |
Functional Keywords | proteinase, zinc-endopeptidase, proteinase inhibitor, complex, mmps (matrix metallo proteinases) timps (tissue inhibitor of metallo proteinases), metzincins, complex (metalloprotease-inhibitor), complex (metalloprotease-inhibitor) complex, complex (metalloprotease/inhibitor) |
Biological source | Homo sapiens (human) More |
Cellular location | Secreted, extracellular space, extracellular matrix (Probable): P08254 Secreted: P01033 |
Total number of polymer chains | 4 |
Total formula weight | 80816.33 |
Authors | Bode, W.,Maskos, K.,Gomis-Rueth, F.-X.,Nagase, H. (deposition date: 1997-06-06, release date: 1998-10-14, Last modification date: 2021-11-03) |
Primary citation | Gomis-Ruth, F.X.,Maskos, K.,Betz, M.,Bergner, A.,Huber, R.,Suzuki, K.,Yoshida, N.,Nagase, H.,Brew, K.,Bourenkov, G.P.,Bartunik, H.,Bode, W. Mechanism of inhibition of the human matrix metalloproteinase stromelysin-1 by TIMP-1. Nature, 389:77-81, 1997 Cited by PubMed: 9288970DOI: 10.1038/37995 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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