1TX4
RHO/RHOGAP/GDP(DOT)ALF4 COMPLEX
Summary for 1TX4
Entry DOI | 10.2210/pdb1tx4/pdb |
Descriptor | P50-RHOGAP, TRANSFORMING PROTEIN RHOA, MAGNESIUM ION, ... (6 entities in total) |
Functional Keywords | complex (gtpase activation-proto-oncogene), gtpase, transition state, gap, complex(gtpase activatn-proto-oncogene) complex, complex(gtpase activatn/proto-oncogene) |
Biological source | Homo sapiens (human) More |
Cellular location | Cytoplasm: Q07960 Cell membrane; Lipid-anchor; Cytoplasmic side: P61586 |
Total number of polymer chains | 2 |
Total formula weight | 43190.24 |
Authors | Rittinger, K.,Walker, P.A.,Smerdon, S.J.,Gamblin, S.J. (deposition date: 1997-07-29, release date: 1998-09-16, Last modification date: 2024-05-22) |
Primary citation | Rittinger, K.,Walker, P.A.,Eccleston, J.F.,Smerdon, S.J.,Gamblin, S.J. Structure at 1.65 A of RhoA and its GTPase-activating protein in complex with a transition-state analogue. Nature, 389:758-762, 1997 Cited by PubMed: 9338791DOI: 10.1038/39651 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.65 Å) |
Structure validation
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