1TX4
RHO/RHOGAP/GDP(DOT)ALF4 COMPLEX
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | P50-RHOGAP | polymer | 198 | 22586.8 | 1 | UniProt (Q07960) Pfam (PF00620) | Homo sapiens (human) | GTPASE-ACTIVATING PROTEIN RHOGAP |
| 2 | B (B) | TRANSFORMING PROTEIN RHOA | polymer | 177 | 20032.9 | 1 | UniProt (P61586) Pfam (PF00071) | Homo sapiens (human) | |
| 3 | C (B) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) PubChem (888) | |||
| 4 | D (B) | TETRAFLUOROALUMINATE ION | non-polymer | 103.0 | 1 | Chemie (ALF) PubChem (5311325) | |||
| 5 | E (B) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 1 | Chemie (GDP) PubChem (136073927) PubChem (135398619) PubChem (135402030) PubChem (135431654) PubChem (135566337) PubChem (135760556) PubChem (136026707) PubChem (136053418) PubChem (136663964) PubChem (136664748) PubChem (136759848) PubChem (136759849) PubChem (136759850) PubChem (136836636) PubChem (136847074) PubChem (172898537) | |||
| 6 | F, G (A, B) | water | water | 18.0 | 497 | Chemie (HOH) |
Sequence modifications
A: 37 - 234 (UniProt: Q07960)
B: 3 - 179 (UniProt: P61586)
| PDB | External Database | Details |
|---|---|---|
| Ala 113 | Glu 310 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Asn 25 | Phe 25 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 42619.8 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 570.5 | |
| All* | Total formula weight | 43190.2 |
