1TX4
RHO/RHOGAP/GDP(DOT)ALF4 COMPLEX
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | P50-RHOGAP | polymer | 198 | 22586.8 | 1 | UniProt (Q07960) Pfam (PF00620) | Homo sapiens (human) | GTPASE-ACTIVATING PROTEIN RHOGAP |
| 2 | B (B) | TRANSFORMING PROTEIN RHOA | polymer | 177 | 20032.9 | 1 | UniProt (P61586) Pfam (PF00071) | Homo sapiens (human) | |
| 3 | C (B) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 4 | D (B) | TETRAFLUOROALUMINATE ION | non-polymer | 103.0 | 1 | Chemie (ALF) | |||
| 5 | E (B) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 1 | Chemie (GDP) | |||
| 6 | F, G (A, B) | water | water | 18.0 | 497 | Chemie (HOH) |
Sequence modifications
A: 37 - 234 (UniProt: Q07960)
B: 3 - 179 (UniProt: P61586)
| PDB | External Database | Details |
|---|---|---|
| Ala 113 | Glu 310 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Asn 25 | Phe 25 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 42619.8 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 570.5 | |
| All* | Total formula weight | 43190.2 |
