1TOZ
NMR structure of the human NOTCH-1 ligand binding region
Summary for 1TOZ
Entry DOI | 10.2210/pdb1toz/pdb |
Related | 1EMO 1HJ7 1LMJ |
Descriptor | Neurogenic locus notch homolog protein 1 (1 entity in total) |
Functional Keywords | notch, egf, calcium binding, ligand binding, module, signaling protein |
Biological source | Homo sapiens (human) |
Cellular location | Cell membrane; Single-pass type I membrane protein (By similarity). Notch 1 intracellular domain: Nucleus (By similarity): P46531 |
Total number of polymer chains | 1 |
Total formula weight | 12600.01 |
Authors | Hambleton, S.,Valeyev, N.Y.,Muranyi, A.,Knott, V.,Werner, J.M.,Mcmichael, A.J.,Handford, P.A.,Downing, A.K. (deposition date: 2004-06-15, release date: 2004-10-12, Last modification date: 2021-11-10) |
Primary citation | Hambleton, S.,Valeyev, N.V.,Muranyi, A.,Knott, V.,Werner, J.M.,McMichael, A.J.,Handford, P.A.,Downing, A.K. Structural and functional properties of the human notch-1 ligand binding region STRUCTURE, 12:2173-2183, 2004 Cited by PubMed: 15576031DOI: 10.1016/j.str.2004.09.012 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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