1TFC

CRYSTAL STRUCTURE OF THE LIGAND-BINDING DOMAIN OF THE ESTROGEN-RELATED RECEPTOR GAMMA IN COMPLEX WITH A STEROID RECEPTOR COACTIVATOR-1 PEPTIDE

Summary for 1TFC

Entry DOI	10.2210/pdb1tfc/pdb
Related	1KV6 1S9P 1S9Q
Descriptor	Estrogen-related receptor gamma, steroid receptor coactivator-1 (3 entities in total)
Functional Keywords	transcriptionally active conformation in absence of ligand, transcription
Biological source	Homo sapiens (human) More
Cellular location	Nucleus (Probable): P62508 Nucleus (By similarity): Q15788
Total number of polymer chains	4
Total formula weight	60326.03
Authors	Greschik, H.,Flaig, R.,Renaud, J.P.,Moras, D. (deposition date: 2004-05-27, release date: 2004-07-27, Last modification date: 2023-08-23)
Primary citation	Greschik, H.,Flaig, R.,Renaud, J.P.,Moras, D. Structural Basis for the Deactivation of the Estrogen-related Receptor {gamma} by Diethylstilbestrol or 4-Hydroxytamoxifen and Determinants of Selectivity. J.Biol.Chem., 279:33639-33646, 2004 Cited by PubMed: 15161930 DOI: 10.1074/jbc.M402195200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.4 Å)

Structure validation