1TFC

CRYSTAL STRUCTURE OF THE LIGAND-BINDING DOMAIN OF THE ESTROGEN-RELATED RECEPTOR GAMMA IN COMPLEX WITH A STEROID RECEPTOR COACTIVATOR-1 PEPTIDE

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Estrogen-related receptor gamma	polymer	251	28386.9	2	UniProt (P62508) Pfam (PF00104)	Homo sapiens (human)	Estrogen receptor related protein 3, ERR gamma-2
2	C, D (C, D)	steroid receptor coactivator-1	polymer	15	1776.1	2	UniProt (Q15788)		SRC-1; NUCLEAR RECEPTOR COACTIVATOR 1; SRC-A/NCOA-1
3	E, F (A, B)	water	water		18.0	40	Chemie (HOH)

Sequence modifications

A, B: 229 - 458 (UniProt: P62508)

PDB	External Database	Details
Met 208	-	expression tag
Gly 209	-	expression tag
Ser 210	-	expression tag
Ser 211	-	expression tag
His 212	-	expression tag
His 213	-	expression tag
His 214	-	expression tag
His 215	-	expression tag
His 216	-	expression tag
His 217	-	expression tag
Ser 218	-	expression tag
Ser 219	-	expression tag
Gly 220	-	expression tag
Leu 221	-	expression tag
Val 222	-	expression tag
Pro 223	-	expression tag
Arg 224	-	expression tag
Gly 225	-	expression tag
Ser 226	-	expression tag
His 227	-	expression tag
Met 228	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	60326.0
All*	Total formula weight	60326.0

*Water molecules are not included.