1T9R

Catalytic Domain Of Human Phosphodiesterase 5A

Summary for 1T9R

Entry DOI	10.2210/pdb1t9r/pdb
Related	1T9S 1TAZ 1TB5 1TB7 1TBB 1TBF
Descriptor	cGMP-specific 3',5'-cyclic phosphodiesterase, ZINC ION, PHOSPHATE ION, ... (5 entities in total)
Functional Keywords	hydrolase, pde5a
Biological source	Homo sapiens (human)
Total number of polymer chains	1
Total formula weight	42461.82
Authors	Zhang, K.Y.J.,Card, G.L.,Suzuki, Y.,Artis, D.R.,Fong, D.,Gillette, S.,Hsieh, D.,Neiman, J.,West, B.L.,Zhang, C.,Milburn, M.V.,Kim, S.-H.,Schlessinger, J.,Bollag, G. (deposition date: 2004-05-18, release date: 2004-08-03, Last modification date: 2024-02-14)
Primary citation	Zhang, K.Y.J.,Card, G.L.,Suzuki, Y.,Artis, D.R.,Fong, D.,Gillette, S.,Hsieh, D.,Neiman, J.,West, B.L.,Zhang, C.,Milburn, M.V.,Kim, S.-H.,Schlessinger, J.,Bollag, G. A Glutamine Switch Mechanism for Nucleotide Selectivity by Phosphodiesterases Mol.Cell, 15:279-286, 2004 Cited by PubMed: 15260978 DOI: 10.1016/j.molcel.2004.07.005 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation