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1T9R

Catalytic Domain Of Human Phosphodiesterase 5A

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
cGMP-specific 3',5'-cyclic phosphodiesterasepolymer36642109.31UniProt (O76074)
Pfam (PF00233)
Homo sapiens (human)CGB-PDE, cGMP-binding cGMP-specific phosphodiesterase
2B
(A)
ZINC IONnon-polymer65.41Chemie (ZN)
3C
(A)
PHOSPHATE IONnon-polymer95.01Chemie (PO4)
PubChem (1061)
4D
(A)
CITRIC ACIDnon-polymer192.11Chemie (CIT)
PubChem (311)
5E
(A)
waterwater18.090Chemie (HOH)
Sequence modifications
A: 531 - 875 (UniProt: O76074)
PDBExternal DatabaseDetails
Met 510-expression tag
Gly 511-expression tag
Ser 512-expression tag
Ser 513-expression tag
His 514-expression tag
His 515-expression tag
His 516-expression tag
His 517-expression tag
His 518-expression tag
His 519-expression tag
Ser 520-expression tag
Ser 521-expression tag
Gly 522-expression tag
Leu 523-expression tag
Val 524-expression tag
Pro 525-expression tag
Arg 526-expression tag
Gly 527-expression tag
Ser 528-expression tag
His 529-expression tag
Met 530-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight42109.3
Non-Polymers*Number of molecules3
Total formula weight352.5
All*Total formula weight42461.8
*Water molecules are not included.

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PDB entries from 2026-04-01

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