1T79

Crystal structure of the androgen receptor ligand binding domain in complex with a FxxLW motif

Summary for 1T79

Entry DOI	10.2210/pdb1t79/pdb
Related	1T73 1T74 1T76 1T7F 1T7M 1T7R 1T7T
Descriptor	Androgen receptor, FxxLW motif peptide, 5-ALPHA-DIHYDROTESTOSTERONE, ... (4 entities in total)
Functional Keywords	nuclear receptor, transcription factor, ligand binding domain, af-2, androgen, testosterone, dht, alpha-helical sandwich, hormone-growth factor receptor complex, hormone/growth factor receptor
Biological source	Pan troglodytes (chimpanzee) More
Cellular location	Nucleus (By similarity): O97775
Total number of polymer chains	2
Total formula weight	33291.81
Authors	Hur, E.,Pfaff, S.J.,Payne, E.S.,Gron, H.,Buehrer, B.M.,Fletterick, R.J. (deposition date: 2004-05-08, release date: 2004-08-31, Last modification date: 2024-02-14)
Primary citation	Hur, E.,Pfaff, S.J.,Payne, E.S.,Gron, H.,Buehrer, B.M.,Fletterick, R.J. Recognition and accommodation at the androgen receptor coactivator binding interface. Plos Biol., 2:E274-E274, 2004 Cited by PubMed: 15328534 DOI: 10.1371/journal.pbio.0020274 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation