1T08
Crystal structure of beta-catenin/ICAT helical domain/unphosphorylated APC R3
Summary for 1T08
Entry DOI | 10.2210/pdb1t08/pdb |
Descriptor | Beta-catenin, Beta-catenin-interacting protein 1, Adenomatous polyposis coli protein, ... (4 entities in total) |
Functional Keywords | beta-catenin; wnt signal; apc; 20mer repeat; wnt signaling, cell adhesion-cell cycle complex, cell adhesion/cell cycle |
Biological source | Homo sapiens (human) More |
Cellular location | Cytoplasm: P35222 Cytoplasm (By similarity): Q9NSA3 Cell junction, adherens junction: P25054 |
Total number of polymer chains | 3 |
Total formula weight | 63456.42 |
Authors | Ha, N.-C.,Tonozuka, T.,Stamos, J.L.,Weis, W.I. (deposition date: 2004-04-07, release date: 2004-10-12, Last modification date: 2023-08-23) |
Primary citation | Ha, N.-C.,Tonozuka, T.,Stamos, J.L.,Choi, H.J.,Weis, W.I. Mechanism of phosphorylation-dependent binding of APC to beta-catenin and its role in beta-catenin degradation Mol.Cell, 15:511-521, 2004 Cited by PubMed: 15327768DOI: 10.1016/j.molcel.2004.08.010 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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