1T02
Crystal structure of a Statin bound to class II HMG-CoA reductase
Summary for 1T02
Entry DOI | 10.2210/pdb1t02/pdb |
Related | 1qax 1qay 1r31 1r7i |
Descriptor | 3-hydroxy-3-methylglutaryl-coenzyme A reductase, (3R,5R)-7-((1R,2R,6S,8R,8AS)-2,6-DIMETHYL-8-{[(2R)-2-METHYLBUTANOYL]OXY}-1,2,6,7,8,8A-HEXAHYDRONAPHTHALEN-1-YL)-3,5-DIHYDROXYHEPTANOIC ACID, SULFATE ION, ... (4 entities in total) |
Functional Keywords | statin, hmg-coa reductase, complex, oxidoreductase |
Biological source | Pseudomonas mevalonii |
Total number of polymer chains | 2 |
Total formula weight | 91801.10 |
Authors | Tabernero, L.,Rodwell, V.W.,Stauffacher, C. (deposition date: 2004-04-07, release date: 2004-08-03, Last modification date: 2023-08-23) |
Primary citation | Tabernero, L.,Rodwell, V.W.,Stauffacher, C.V. Crystal structure of a statin bound to a class II hydroxymethylglutaryl-CoA reductase. J.Biol.Chem., 278:19933-19938, 2003 Cited by PubMed: 12621048DOI: 10.1074/jbc.M213006200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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