1STH

TWO DISTINCTLY DIFFERENT METAL BINDING MODES ARE SEEN IN X-RAY CRYSTAL STRUCTURES OF STAPHYLOCOCCAL NUCLEASE-COBALT(II)-NUCLEOTIDE COMPLEXES

Summary for 1STH

DescriptorSTAPHYLOCOCCAL NUCLEASE, COBALT (II) ION, THYMIDINE-3',5'-DIPHOSPHATE, ... (4 entities in total)
Functional Keywordshydrolase (phosphoric diester)
Biological sourceStaphylococcus aureus
Cellular locationNuclease A: Secreted. Nuclease B: Membrane P00644
Total number of polymer chains1
Total molecular weight17304.45
Authors
Loll, P.J.,Quirk, S.,Lattman, E.E. (deposition date: 1994-10-27, release date: 1995-02-27, Last modification date: 2011-07-13)
Primary citation
Loll, P.J.,Quirk, S.,Lattman, E.E.,Garavito, R.M.
X-ray crystal structures of staphylococcal nuclease complexed with the competitive inhibitor cobalt(II) and nucleotide.
Biochemistry, 34:4316-4324, 1995
PubMed: 7703245 (PDB entries with the same primary citation)
DOI: 10.1021/bi00013a021
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.85 Å)
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Structure validation

ClashscoreRamachandran outliersSidechain outliersRSRZ outliers5 2.2% 8.8% 3.7%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
171916
PDB entries from 2020-12-02