1SM3

CRYSTAL STRUCTURE OF THE TUMOR SPECIFIC ANTIBODY SM3 COMPLEX WITH ITS PEPTIDE EPITOPE

1SM3 の概要

• エントリーDOI: 10.2210/pdb1sm3/pdb
• 分子名称: SM3 ANTIBODY, PEPTIDE EPITOPE, CADMIUM ION, ... (6 entities in total)
• 機能のキーワード: antibody, peptide antigen, antitumor antibody, complex (antibody-peptide epitope), complex (antibody-peptide epitope) complex, complex (antibody/peptide epitope)
• 由来する生物種: Mus musculus (house mouse); 詳細
• 細胞内の位置: Apical cell membrane; Single-pass type I membrane protein. Isoform 5: Secreted. Isoform 7: Secreted. Isoform 9: Secreted. Mucin-1 subunit beta: Cell membrane: P15941
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 48838.30

構造登録者

Dokurno, P.,Bates, P.A.,Band, H.A.,Stewart, L.M.D.,Lally, J.M.,Burchell, J.M.,Taylor-Papadimitriou, J.,Sternberg, M.J.E.,Snary, D.,Freemont, P.S. (登録日: 1997-12-23, 公開日: 1999-03-23, 最終更新日: 2023-08-09)

• 主引用文献: Dokurno, P.,Bates, P.A.,Band, H.A.,Stewart, L.M.,Lally, J.M.,Burchell, J.M.,Taylor-Papadimitriou, J.,Snary, D.,Sternberg, M.J.,Freemont, P.S.; Crystal structure at 1.95 A resolution of the breast tumour-specific antibody SM3 complexed with its peptide epitope reveals novel hypervariable loop recognition.; J.Mol.Biol., 284:713-728, 1998; PubMed: 9826510; DOI: 10.1006/jmbi.1998.2209

実験手法

X-RAY DIFFRACTION (1.95 Å)