1SHZ
Crystal Structure of the p115RhoGEF rgRGS Domain in A Complex with Galpha(13):Galpha(i1) Chimera
Summary for 1SHZ
Entry DOI | 10.2210/pdb1shz/pdb |
Related | 1AGR 1AZS 1FQJ 1IAP |
Descriptor | Guanine Nucleotide-Binding Protein Galpha(13):Galpha(i1) Chimera, Rho guanine nucleotide exchange factor 1, MAGNESIUM ION, ... (6 entities in total) |
Functional Keywords | signal transduction, protein complex, signaling protein |
Biological source | Rattus norvegicus (house mouse, Norway rat) More |
Cellular location | Nucleus: P10824 Cytoplasm : Q92888 |
Total number of polymer chains | 4 |
Total formula weight | 133115.10 |
Authors | Chen, Z.,Singer, W.D.,Sternweis, P.C.,Sprang, S.R. (deposition date: 2004-02-26, release date: 2005-01-18, Last modification date: 2023-08-23) |
Primary citation | Chen, Z.,Singer, W.D.,Sternweis, P.C.,Sprang, S.R. Structure of the p115RhoGEF rgRGS domain-Galpha13/i1 chimera complex suggests convergent evolution of a GTPase activator. Nat.Struct.Mol.Biol., 12:191-197, 2005 Cited by PubMed: 15665872DOI: 10.1038/nsmb888 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.85 Å) |
Structure validation
Download full validation report