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1SHZ

Crystal Structure of the p115RhoGEF rgRGS Domain in A Complex with Galpha(13):Galpha(i1) Chimera

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, DGuanine Nucleotide-Binding Protein Galpha(13):Galpha(i1) Chimerapolymer34039640.22UniProt (P10824)
UniProt (P27601)
Pfam (PF00503)
In PDB
Rattus norvegicus (house mouse Norway rat)
2C, FRho guanine nucleotide exchange factor 1polymer23326346.92UniProt (Q92888)
Pfam (PF09128)
In PDB
Homo sapiens (human)p115-RhoGEF, p115RhoGEF, 115 kDa guanine nucleotide exchange factor, Sub1.5
3A, DMAGNESIUM IONnon-polymer24.32Chemie (MG)
4A, DTETRAFLUOROALUMINATE IONnon-polymer103.02Chemie (ALF)
5A, DGUANOSINE-5'-DIPHOSPHATEnon-polymer443.22Chemie (GDP)
6waterwater18.084Chemie (HOH)
Sequence modifications
A, D: 37 - 63 (UniProt: P10824)
A, D: 64 - 207 (UniProt: P27601)
A, D: 208 - 233 (UniProt: P10824)
A, D: 234 - 235 (UniProt: P27601)
A, D: 236 - 253 (UniProt: P10824)
A, D: 254 - 262 (UniProt: P27601)
A, D: 263 - 376 (UniProt: P10824)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight131974.1
Non-Polymers*Number of molecules6
Total formula weight1141.0
All*Total formula weight133115.1
*Water molecules are not included.

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PDB entries from 2024-07-17

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