1SCN
INACTIVATION OF SUBTILISIN CARLSBERG BY N-(TERT-BUTOXYCARBONYL-ALANYL-PROLYL-PHENYLALANYL)-O-BENZOL HYDROXYLAMINE: FORMATION OF COVALENT ENZYME-INHIBITOR LINKAGE IN THE FORM OF A CARBAMATE DERIVATIVE
Summary for 1SCN
Entry DOI | 10.2210/pdb1scn/pdb |
Related PRD ID | PRD_000260 |
Descriptor | SUBTILISIN CARLSBERG, N-(tert-butoxycarbonyl)-L-alanyl-N-[(1R)-1-(carboxyamino)-2-phenylethyl]-L-prolinamide, CALCIUM ION, ... (5 entities in total) |
Functional Keywords | hydrolase-hydrolase inhibitor complex, serine proteinase, hydrolase/hydrolase inhibitor |
Biological source | Bacillus licheniformis |
Cellular location | Secreted: P00780 |
Total number of polymer chains | 1 |
Total formula weight | 28026.05 |
Authors | Steinmetz, A.C.U.,Demuth, H.-U.,Ringe, D. (deposition date: 1994-03-02, release date: 1994-08-31, Last modification date: 2017-11-29) |
Primary citation | Steinmetz, A.C.,Demuth, H.U.,Ringe, D. Inactivation of subtilisin Carlsberg by N-((tert-butoxycarbonyl)alanylprolylphenylalanyl)-O-benzolhydroxyl- amine: formation of a covalent enzyme-inhibitor linkage in the form of a carbamate derivative. Biochemistry, 33:10535-10544, 1994 Cited by PubMed: 8068694DOI: 10.1021/bi00200a040 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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